Limb-threatening or essential limb ischemia (CLI) is manifested by Long-term (over two weeks) ischemic rest soreness, ischemic wounds or tissue decline, or gangrene in a single or equally legs. Ischemic rest discomfort ordinarily takes place before long immediately after slipping asleep; the individual is awakened by burning ache or numbness https://www.sgvascularctr.com/treatment-of-peripheral-artery-disease-pad-in-singapore-a-comprehensive-guide/