Pentobarbital raises toxicity of buprenorphine, extended-acting injection by pharmacodynamic synergism. Modify Therapy/Watch Carefully. Coadministration of buprenorphine and benzodiazepines or other CNS depressants boosts possibility of adverse reactions including overdose, respiratory depression, and death. Cessation of benzodiazepines or other CNS depressants is favored normally. Dr... https://robertd958kyn1.blogsumer.com/profile